Yes, according to some random guy on the internet. Here’s a made-up quote purportedly from Matt Groening:
Die hard fans may get a long overdue recurring gag. Remember the episode where Lester and Eliza saved the day instead of Bart and Lisa? That was disturbing, and I personally expected them to come back and wreak more havoc. A decade later, we may finally get closure. “I think we put them in The Simpsons movie. They were in one draft. I’m not sure if they survive.”
3/8/2007 UPDATE: I guess the quote wasn’t made up! You can see it here in this interview with Crave Online.